Surface Binding Energy Landscapes Affect Phosphodiesterase Isoform-Specific Inhibitor Selectivity
نویسندگان
چکیده
منابع مشابه
Identification of RNA-binding sites in artemin based on docking energy landscapes and molecular dynamics simulation
There are questions concerning the functions of artemin, an abundant stress protein found in Artemiaduring embryo development. It has been reported that artemin binds RNA at high temperatures in vitro, suggesting an RNA protective role. In this study, we investigated the possibility of the presence of RNA-bindingsites and their structural properties in artemin, using docking energy ...
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*Intramural Research Support Program, Science Applications International Corporation, Laboratory of Experimental and Computational Biology, and †Laboratory of Experimental and Computational Biology, National Cancer Institute–Frederick Cancer Research and Development Center, Building 469, Room 151, Frederick, MD 21702; and ‡Sackler Institute of Molecular Medicine, Sackler Faculty of Medicine, Te...
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ژورنال
عنوان ژورنال: Computational and Structural Biotechnology Journal
سال: 2019
ISSN: 2001-0370
DOI: 10.1016/j.csbj.2018.11.009